报告题目：Fluorescent Sensing and Logic Systems

报告人：Prof. AP de Silva

主持人：胡玥

时间：2018年7月2日上午9:30-10:30

地点：武汉光电国家研究中心A302

报告摘要：One of the main principles underlying fluorescent sensors is based on PET (photoinduced electron transfer), according to which a switching ‘on’ of fluorescence in response to chemical and biochemical analytes can be designed. Since its generalization in Colombo, Sri Lanka, it has now grown to involve 500 laboratories around the world. Some of these sensor systems are serving in critical care units in hospitals and in ambulances, performing blood diagnostics. These form the basis of a half-billion-dollar industry. Other sensors visualize intracellular players. Yet others map species distributions in nanometric spaces near membranes. These spaces are too small for the tiniest silicon-based wireless devices to enter. Our introduction of molecular logic gates from Belfast, Northern Ireland, allows us to build more complex sensors and micro-object identification systems. More complex logic operations and even human-scale computations, e.g. edge detection of objects and outline drawing, are now achieved by molecular systems. 710 laboratories have contributed to this field so far. A short video is available at www.youtube.com/watch?v=sLGnZDP5Ecg.

报告人简介：A.P de Silva 教授，任教于贝尔法斯特女王大学，是国际上有重要影响的知名科学家，主要研究领域是有机荧光探针分子的设计合成。他是最早从事分子逻辑计算相关研究的科学家之一，有着非常深厚的研究造诣，并在1993年首次创新地提出具有分子属性的逻辑门，首次提出用光诱导电子转移机制PET (photo-induced electron transfer)设计荧光探针分子，得到了极为广泛的应用；其实验室开发的医用血液分析仪被Optimedical Inc.公司购买，产生了1亿美元的市场价值。曾获得2008年英国皇家学会Sensors award。在Nature, Nature Nano, Nature Materials, Chem Rev等发表多篇高水平论文，2013年出版专著《分子逻辑计算》，2014年被译为中文和日语两种语言，中文译者为田禾院士。